Switching gears entirely from the arctic, the Chicago Tribune ran
my story today on new autism research at UIC. A team of scientists is looking at the role of serotonin in autism, specifically its connection to the trait called "insistence on sameness," which about a quarter of people with autism have. They have a rigidity of routine and insist that daily activities occur in exactly the same way each time. When something goes awry, it can induce anything from anxiety to aggression.
The researchers are using a combination of genetic testing, experimental medication and high-resolution brain scans to try to understand this one piece of the puzzle that is autism. (Contact Kate Ernstrom’s at kernstrom@psych.uic.edu or 312-996-7835 for more information about participating in the study.)
In addition to explaining the research, I interviewed Alec Kedziora, a 17-year-old boy with autism who was part of the study.
Alec was articulate and eager to share his thoughts about having autism and how he's improved since taking the antidepressant that he was prescribed as part of the study. One of the great frustrations for families of people with autism, as well as for doctors treating them, is that people with the syndrome often can't explain what they're thinking or feeling. Talking with Alec was fascinating. Plus he has a great sense of humor and knew how to charm a journalist, often remarking "good question!" after I asked him what was different about his life since he started on the medication or what the hardest thing is about having autism.
I wasn't able to fit in nearly as much about Alec into the story as I wanted, so here is some of what ended up on the cutting room floor:
Alec Kedziora said very little until he was 5 years old. He used drawings to express himself.
Sometimes they were communiqués to his parents, Joe and NiCole Kedziora of Orland Park, like the time he drew a picture of the orange mini-golf ball he wanted to use. Other times they were purely creative pursuits, including his habit of drawing scenes from Disney movies in magic marker on the walls of his house.
Alec was diagnosed with autism when he was 3. He started talking more as he grew, but other problems appeared. He developed a rigidity that dictated that certain routines and situations stay exactly the same.
He was picky about foods, refusing anything new and subsisting on a self-selected diet heavy on Cheerios, Chex Mix and bacon. He insisted that all the doors in the house be kept closed. His morning routine was identical every day and timed perfectly. If he overslept by even a few minutes he would be late for school.
Though he was an affectionate, sweet kid, if a routine went awry, Alec often threw a fit and sometimes banged his head against a desk or wall.
In eighth grade he made a still-life drawing in art class. In soft colors, it depicts a photo of himself with his younger sister, Chloe, a jewelry box he gave his mom, and a stress ball he carried everywhere to help calm himself down. On the bottom he wrote: "I have often dreamed to have peace and happiness."

Around freshman year of high school things took a turn for the worse. His frustration used to be channeled into tears; suddenly he became aggressive.
His parents blame a combination of puberty and starting a new school with unfamiliar people and schedules. One day a boy taunted Alec a couple inches from his face, assuming Alec wouldn't understand. Alec shoved him and the two got in a fight. There were a handful of similar incidents that fall.
"We were mortified," his mother, NiCole, says.
Even Alec realized he was acting badly.
"I was suffering," Alec says. "I was sad about it."
His parents say he would apologize later for getting upset.
"It would be heartbreaking," Joe says. "He would say, 'I'm sorry I'm so difficult. I'm harder than other kids. I'm sorry I'm so sensitive. I can't let it go. I can't move on.'"
Alec's life changed immediately and dramatically as soon as he started taking the antidepressant Lexapro.
"This medicine can calm me down," he says. The best part of the Lexapro, he says, is "getting through my day so well."
He's able to vary his routine. He can change the order of dinner and a shower, something that used to be fixed, and gets to school on time if he oversleeps. He's become an adventurous eater, trying cheddar broccoli soup, which has a consistency that grossed him out in the past. And he's open to learning new things. Alec has played lacrosse for four years, but he's more coachable on Lexapro.
Mostly, he's able to keep his frustration in check and talk through his feelings if something upsets him. He hasn't gotten into fights at school since starting the medication.
He's still an avid drawer, and his room is filled with precise sketches of comic book characters he invented, haunted mansions and fairy tale castles.
He was excited to be part of the UIC study, he says, because it meant, "that I could help children who have autism disabilities."
He particularly enjoyed looking at the images from his brain scans.
"I got to see my own brain," he says, "where there is autism in it."